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Lower-intervention assisted conception

Intrauterine Insemination (IUI)

Washed, motile-prepared sperm placed directly into the uterus at the precise ovulation window — appropriate for mild male factor, unexplained infertility and donor cycles.

Indicative pricing
₹15,000–₹25,000 · per cycle

IUI is often dismissed as 'IVF lite', but used in the right couple it has genuine value: lower cost, no anaesthesia, minimal medication, and a 12–18% per-cycle success rate when the indication is correct. The mistake is doing 6 IUIs when 2 would have been enough to know it isn't working.

Who it's for
  • Mild male factor (count > 10 million motile post-wash)
  • Cervical factor or unexplained infertility under 35
  • Single women or same-sex couples using donor sperm (ART Act compliant)
  • Couples who haven't completed family workup but want an interim attempt
What's included
  • Cycle monitoring with letrozole or gonadotropins
  • Density-gradient sperm wash and preparation
  • Trigger injection at optimal follicle size
  • IUI procedure 36 hours later — 5-minute, painless
  • Luteal support and pregnancy test
The process

How a intrauterine insemination (iui) pathway unfolds.

01
Stimulation
Mild stimulation to grow 1–2 follicles — not more, to avoid multiples.
02
Sperm prep
Sample produced at the clinic, washed and concentrated within 1 hour.
03
Insemination
Soft catheter placement of prepared sperm into the uterus. No sedation needed.
04
Test
Beta-hCG 14 days later.

When IUI is the right choice

IUI works best when the female partner is under 35, has at least one open tube, ovulates predictably (or can be made to), and the male partner has a post-wash motile count above 10 million. Cervical factor, mild male factor, unexplained infertility of short duration and donor sperm cycles all do well with IUI.

It does not work well — and we will tell you so — when there is bilateral tubal block, severe male factor, advanced endometriosis, or a long history of failed monitored cycles. Trying IUI in those settings just delays the move to IVF.

How many cycles to try?

The evidence supports 3 IUI cycles maximum for couples under 35 — beyond that, success per cycle drops sharply and IVF becomes more cost-effective per live birth. For women over 35, we usually recommend no more than 2 IUIs before reviewing. For women over 38, we often recommend skipping IUI altogether and going straight to IVF, because the time cost is too high.

The lab side of IUI

What goes into the uterus matters more than the procedure itself. Density-gradient sperm preparation in our embryology lab removes seminal plasma, debris, dead sperm and white cells, leaving a concentrated pellet of motile sperm. For high-DFI cases, we offer MACS-prepared sperm even for IUI cycles. The wash is timed so that insemination happens 60–90 minutes after preparation — fresh, motile, ready.

Common questions

Patients usually ask…

Is IUI painful?

No — it feels like a slightly longer pap smear. Most patients drive themselves home afterwards and return to work within an hour.

What's the success rate per cycle?

12–18% under age 35, 6–10% over 35, 2–4% over 40 — which is why we don't recommend it indefinitely.

Can we use donor sperm?

Yes — fully permitted under the ART Act 2021, with sperm sourced only from registered ART banks. We handle the matching and consent paperwork.

Talk to Dr. Sana about intrauterine insemination (iui).

45-minute consultation, booked directly with Dr. Sana on WhatsApp. She consults at Apollo Fertility, Hyderabad. No referral needed.